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KMID : 0359319940340020369
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Korean Journal of Veterinary Research
1994 Volume.34 No. 2 p.369 ~ p.374
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Acute and subacute toxicity of folpet to fingerings of common carp , Cyprinus carpio and goldfish , Carassius auratus
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Abstract
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The acute and subacute toxicity of fungicide folpet was evaluated in fingerings of common carp, Cyprinus carpio and goldfish, Carrassius auratus. Dipping of fishes for acute toxicity was performed for a period of 24h, and the TLm value(median tolerance limit) was 1.52 ppm in common carp and 1.45 ppm in goldfish.
Severe damages were observed in various organs and among them, clubbing of gill lamella, lytic degeneration and vacuolation of liver cells, and epithelial edema of renal tubules were relatively prominent. The most significant changes were hyperbasophilic foci of liver cells in subacute toxicity test and these can imply the possibility of hepatocarcinogenecity of folpet.
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